We often make the wrong trade-offs. Many of us make the mistake of swapping fat for the empty calories of sugar and refined carbohydrates. Instead of eating whole-fat yoghurt, for example, we eat low- or no-fat versions that are packed with sugar to make up for the loss of taste. Or we swap our fatty breakfast bacon for a muffin or donut that causes rapid spikes in blood sugar.

Cancer, a very common and sometimes fatal cause of unexplained (idiopathic) weight loss. About one-third of unintentional weight loss cases are secondary to malignancy. Cancers to suspect in patients with unexplained weight loss include gastrointestinal, prostate, hepatobiliary (hepatocellular carcinoma, pancreatic cancer), ovarian, hematologic or lung malignancies.

Build more muscle: Cardio gets all the glory for melting fat, but it’s actually far more important to focus on building muscle. It’s pretty simple: Lipolysis happens in the mitochondria of the muscles, so the more muscle you have, the more mitochondria, and the more potential to burn. Plus, the more muscle mass you carry, the more your BMR is burning calories at rest. Strength training is also one of the strongest ways to spark production of testosterone and growth hormone, which both help to break down fat, Seedman adds.

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