Whether you sit or stand at work may play as big a role in your waistline as your fitness routine. Missouri University researchers discovered that inactivity (4 hours or more) causes a near shut- down of an enzyme that controls fat and cholesterol metabolism. To keep this enzyme active and increase your fat-burning, break up long periods of downtime by standing up—for example, while talking on the phone.

A diet that’s low in fat and carbohydrates can improve artery function, according to a 2012 study by Johns Hopkins researchers. After six months, those on the low-carb diet had lost more weight, and at a faster pace. But in both groups, when weight was lost—and especially when belly fat shrank—the arteries were able to expand better, allowing blood to travel more freely. The study shows that you don’t have to cut out all dietary fat to shrink belly fat. For heart health, simply losing weight and exercising seems to be key. 
If you’ve got weight to lose and you want it gone fast, try swapping out your usual proteins in favor of fish. Not only is fish lower in calories than an equivalent amount of beef or chicken, a study published in Obesity reveals study subjects who added omega-3 fatty acids, like those found in fish, to their diets shed more weight and had an easier time keeping it off than those who skipped them.
Intermittent fasting—limiting your eating hours to just eight, say between 10:30 and 6:30—has gained popularity as a way to shake up your metabolism, and it just might work. “There is a lot more research that needs to be done but it does seem to benefit some people, particularly men,” says Angel Planells, RD, a spokesperson for the Academy of Nutrition and Dietetics based in Seattle. Another approach is to fast—or eat next to no calories (500-600 calories total)—two non-consecutive days a week. (You can eat normally the other five days.) The tactic seems to increase fat burning. “When your body isn’t getting fuel, it will start burning fat,” Planells says. Read about this woman’s experience with intermittent fasting.
To prevent that from happening, says Jessica Crandall, RD, a spokesperson for the Academy of Nutrition and Dietetics and personal trainer, aim for between 20 and 30 grams first thing. She likes an egg scramble with veggies, cheese, and black beans or fills to-go coffee cups with a mix of Greek yogurt, chia seeds, nuts, and berries. Don’t miss these 13 things experts won’t tell you about weight loss.
The prevailing formula for a long time on how much fat you’re going to burn was calories in minus calories out, based on your basal metabolic rate (BMR) and exercise efforts, explains strength and performance specialist Joel Seedman, Ph.D., owner of Advanced Human Performance in Atlanta. But with all the different biochemical reactions in the body, hormonal response, and endocrine function, there are an infinite number of factors that can affect how your body is storing and breaking down calories.
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