The upshot of all these chemicals floating around is big trouble for big-bellied guys. In a study at the University of Alabama at Birmingham, researchers took 137 men of all ages and sizes and used seven different measurements to determine their risks of cardiovascular disease. The single best sign of multiple heart-disease risks? No, it wasn't the guys' family histories or their cholesterol profiles. It was the amount of abdominal fat they carried.
The prevailing formula for a long time on how much fat you’re going to burn was calories in minus calories out, based on your basal metabolic rate (BMR) and exercise efforts, explains strength and performance specialist Joel Seedman, Ph.D., owner of Advanced Human Performance in Atlanta. But with all the different biochemical reactions in the body, hormonal response, and endocrine function, there are an infinite number of factors that can affect how your body is storing and breaking down calories.