Historically, fat storage worked well for humans. The energy was stored as small packages of molecules called fatty acids, which are released into the bloodstream for use as fuel by muscles and other organs when there was no food available, or when a predator was chasing us. Fat storage actually conferred a survival advantage in these situations. Those with a tendency to store fat were able to survive longer periods without food and had extra energy for hostile environments.
In other words? "Drinking makes you more likely to eat sh*t," Dr. Seltzer says, referring to drunk foods. At the same time, he stops short of asking patients to quit alcohol cold-turkey to lose weight. Plus, research suggests you don’t have to, as long as your intake is moderate—i.e., less than about a drink a day. "If you drink a glass of wine every night and notice you eat more afterward, eat less early to account for this," he says. "Or, if you’re drinking four glasses of wine a week, drink three instead so you’ll won’t feel such a big difference."
Digestive metabolism, or thermic effect of food (TEF): Simply digesting food—turning carbs into sugar and turning protein into amino acids—typically burns 10 to 15 percent of your daily calories. Digesting protein burns more calories than digesting carbohydrates or fat—about 25 calories for every 100 consumed. Digesting carbohydrates and fat burns about 10 to 15 calories for every 100 consumed.

^ Mann, T; Tomiyama, AJ; Westling, E; Lew, AM; Samuels, B; Chatman, J (April 2007). "Medicare's search for effective obesity treatments: diets are not the answer". The American Psychologist. 62 (3): 220–33. CiteSeerX 10.1.1.666.7484. doi:10.1037/0003-066x.62.3.220. PMID 17469900. In sum, there is little support for the notion that diets ["severely restricting one’s calorie intake"] lead to lasting weight loss or health benefits.
Build more muscle: Cardio gets all the glory for melting fat, but it’s actually far more important to focus on building muscle. It’s pretty simple: Lipolysis happens in the mitochondria of the muscles, so the more muscle you have, the more mitochondria, and the more potential to burn. Plus, the more muscle mass you carry, the more your BMR is burning calories at rest. Strength training is also one of the strongest ways to spark production of testosterone and growth hormone, which both help to break down fat, Seedman adds.
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