"When going out for fast food, I used to get the large-size value meal. Now, I satisfy a craving by ordering just one item: a small order of fries or a six-piece box of chicken nuggets. So far, I've shaved off 16 pounds in seven weeks, and I'm on track to being thinner than my high school self for my 10-year reunion later this year." —Miranda Jarrell, Birmingham, AL
I built this protocol for people who simply won’t take my advice to be patient and eat the Bulletproof Diet while using Bulletproof Intermittent Fasting. It uses biohacking techniques I pioneered on myself to reduce – but not eliminate – the risks of rapid fat loss. It prevents the metabolic harm and brain fog that come with very low-calorie diets (or multiple day fasts), and it does everything I can think of to maintain health in the face of additional toxins.  This is also not intended for people who are already fairly lean (10-14% body fat).  It is designed for obese and severely overweight people who want to lose fat as fast as possible.
If you're dehydrated, it can be hard to tell if you're hungry or just thirsty. If you're craving a mid-day snack, have a glass of water and wait a few minutes before reassessing how hungry you really are. Water also helps food move through your digestive system, lessening feelings of bloating. It's a good idea to keep a water bottle with you throughout the day. Add in cucumber slices or fresh fruit to infuse flavor.
It may seem like a no-brainer that regular exercise can help you burn fat and lose weight. But it's not just about the calories you're burning. It's also about the adaptations your body makes when you exercise on a regular basis. Many of those adaptations lead directly to your ability to burn more fat without even trying. When you exercise regularly:
3. Twist: One foot placed slightly in front of the other with body facing the corner. This should resemble the movement of wringing a towel while taking knees further “inward” and opening body in the opposite direction. Start with knees bent and straighten with the twist by lifting the hip and leading it to the opposite corner.10 reps each side, then 10 again (total of 20, alternating after 10)
So how does this work? A quick run-through: The first tip was to eat low carb. This is because a low-carb diet lowers your levels of the fat-storing hormone insulin, allowing your fat deposits to shrink and release their stored energy. This tends to cause you to want to consume fewer calories than you expend – without hunger – and lose weight. Several of the tips mentioned above are about fine-tuning your diet to better this effect.
Grazing is a surprisingly good idea because it helps you avoid metabolic slowdown. "Your body will be tricked into thinking it's constantly eating, so it will never slow your metabolism down," explains Bauer. Aim for five small meals (200 to 500 calories) a day rather than three large ones. Also try not to go more than four hours without eating — if you eat breakfast at 7am, for example, have a snack at 10am, lunch at noon, another snack at 3pm and dinner at 7pm.
Cardio exerts two benefits: It burns calories and affects hormone levels in the body. Specifically, cardio helps raise levels of norepinephrine. Yet when you do cardio it makes a big difference in how your body handles the hormonal changes. Cardio on an empty stomach allows norepinephrine to readily target fat cells, which triggers maximal fat-burning. On the flip side, if you eat before doing cardio, and particularly if you eat carbs, the fat-blocking hormone insulin rises, making your body less effective at burning fat.
All animal proteins are also a good source of tryptophan, which is a precursor to the neurotransmitter serotonin. “If you struggle with mood or stress, it’s important to boost the production of serotonin to stabilize your mood, curb emotional eating, and keep stress-induced snacking at bay," especially when you’re trying to lose weight, says Cording. But when it comes to portions, opt for a 100 gram serving, which is about the size of a deck of cards, for reference.
That’s a big deal considering time and opportunity are some of the biggest hurdles people face when trying to make fitness a priority. “Everyone is dealing with full schedules and competing priorities, so it’s often difficult to add something new to your routine without trading something else out,” O’Connor says. You’ll still need to shift some things around to make running a serious part of your life, but being able to run right out your front door, free of charge, eliminates some very real roadblocks. (For proof, see: 20 Incredible Stories of Weight Loss Through Running)
As Max explained, fat loss progress is far more "linear" than weight loss progress, with a far more steady development as opposed to a constantly fluctuating one. Putting it into context, Max notes that "our body fat percentage or lean mass does not fluctuate in the instance where we drink a glass of water, or eat a big meal and then step on the scale — only our bodyweight does this."
Some antidepressant medications can cause weight gain, especially the older tricyclic antidepressants (TCAs) such as Tryptizol, Saroten, and Clomipramine; as well as newer drugs such as Remeron (Mirtazapine). Lithium (for manic-depressive disorder) often causes weight gain. The most common antidepressants known as SSRI’s (for example Citalopram and Sertraline) usually don’t impact weight significantly. More on depression
Now that’s out the way, the second thing we should probably discuss is how fast you should be expecting to lose fat. This depends on how much fat you have to lose. The higher your starting levels of body fat, the faster you can expect to lose; conversely, the leaner you start, a slower rate of loss will be best to minimise muscle and strength loss.
Eat small meals more often. In simple terms, eating spurs your metabolism — the process by which your body turns food into energy. Eating more often, then, may kick your metabolism into a higher gear more times per day (e.g., if you eat six times a day, you get six “spikes”). But, you must make sure that eating more often does not also mean eating more; it’s essential that you reduce your overall average daily calories.[3]

Low-calorie diets are also referred to as balanced percentage diets. Due to their minimal detrimental effects, these types of diets are most commonly recommended by nutritionists. In addition to restricting calorie intake, a balanced diet also regulates macronutrient consumption. From the total number of allotted daily calories, it is recommended that 55% should come from carbohydrates, 15% from protein, and 30% from fats with no more than 10% of total fat coming from saturated forms.[citation needed] For instance, a recommended 1,200 calorie diet would supply about 660 calories from carbohydrates, 180 from protein, and 360 from fat. Some studies suggest that increased consumption of protein can help ease hunger pangs associated with reduced caloric intake by increasing the feeling of satiety.[4] Calorie restriction in this way has many long-term benefits. After reaching the desired body weight, the calories consumed per day may be increased gradually, without exceeding 2,000 net (i.e. derived by subtracting calories burned by physical activity from calories consumed). Combined with increased physical activity, low-calorie diets are thought to be most effective long-term, unlike crash diets, which can achieve short-term results, at best. Physical activity could greatly enhance the efficiency of a diet. The healthiest weight loss regimen, therefore, is one that consists of a balanced diet and moderate physical activity.[citation needed]
If you want to keep burning fat, you’ve got to get moving. Whether you’re able to hit the gym first thing in the morning (after your snack from tip #1) or just taking the stairs throughout the day at work and going for a lunchtime walk – the important thing is to get moving and find simple ways to squeeze fitness into your busy day. Since your body will need carbs to recover from your workout, save your larger, healthier meal for afterward.

Sleep quality matters as much as quantity, according to Gillespie. In general, an uninterrupted seven hours is better than 12 hours of tossing and turning. Of course, for new moms or others for whom sleep is hard to come by, naps are better than nothing. But if it’s possible to get your nightly sleep done in a solid block, that’s your best bet, she says.
This may explain why the fat-burning effects of eating more protein were confirmed in a study published in the American Journal of Physiology. One group was fed a high-protein diet (just over 1 gram per pound of body weight per day) while the second group consumed an amount closer to the lower recommendation of the RDA (recommended dietary allowance). The group eating the higher-protein diet burned the most fat.
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